This paper is based on a talk given by Monsignor Felix Machado of the Pontifical Council for Interreligious Dialogue, the Vatican’s central office for the promotion of inter-religious dialogue, in April 2004 at the annual ISKCON Communications Europe Leadership Team meetings near Bergamo, Italy. In this paper Mons. Machado argues that interfaith dialogue does not require difference be ignored for fear of offending. Quite the opposite: he argues that difference must be acknowledged and respected before proper inter-religious understanding can take place, and that ignoring difference is more likely to lead to a breakdown of relations between people of different faiths. Here he examines some of the unique difficulties and opportunities presented by Christian theology in interfaith dialogue and how Christian doctrine regards the diversity of faith that now pervades almost all societies. This paper and the talk it is based on mark a significant development in ISKCON dialogue with other faith traditions, a dialogue that was begun in earnest with the 1999 statement: ISKCON in Relation to People of Faith in God.